anti-nociceptive activity of aqueous-methanolic extract of phytolacca americana growing in iran

نویسندگان

m karami

s saeidnia

n shahabi majd

ma ebrahimzadeh

چکیده

abstract anti-nociceptive activity of aerial parts of phytolacca americana were investigated, using the hot plate method in mice. results of the present study showed that the aqueous methanolic extract of aerial parts of p. americana produced a statistically significant increase in pain threshold after 30 min, in comparison with the control, at adose of 190 mg kg-1 (p<0.001). the activity was comparable to that of morphine (30 mg kg-1 i.p., p> 0.05). the anti-nociceptive activity of p. americana increased until the 60th min (p<0.05 compared to morphine). the results of this study support the extensive use of p. americana in western asia and america. the ld50 of extract following a 14 days acute toxicity study was calculated to be 208 mg kg-1 i.p.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Anti-nociceptive Activity of Aqueous-methanolic Extract of Phytolacca americana Growing in Iran

Abstract Anti-nociceptive activity of aerial parts of Phytolacca americana were investigated, using the hot plate method in mice. Results of the present study showed that the aqueous methanolic extract of aerial parts of P. americana produced a statistically significant increase in pain threshold after 30 min, in comparison with the control, at adose of 190 mg kg-1 (P 0.05). The anti-nociceptiv...

متن کامل

Anti-nociceptive Activity of Aqueous-methanolic Extract of Phytolacca americana Growing in Iran

Abstract Anti-nociceptive activity of aerial parts of Phytolacca americana were investigated, using the hot plate method in mice. Results of the present study showed that the aqueous methanolic extract of aerial parts of P. americana produced a statistically significant increase in pain threshold after 30 min, in comparison with the control, at adose of 190 mg kg-1 (P 0.05). The anti-nociceptiv...

متن کامل

the effect of aqueous extract of garlic on formalin-induced pain in male rats

چکیده اثر عصاره آبی سیر بر درد ناشی از آزمون فرمالین در موش صحرایی نر به کوشش نرگس اسکندری روزبهانی زمینه و هدف: گیاه سیر از خانواده لیلیاسه و گونهallium sativum بومی آسیای میانه بوده و از دوران ،باستان تاکنون به خواص درمانی متفاوت آن مثل: کاهندگی قندخون، کلسترول خون، فشار خون، اثرات مفیدآن بر دستگاه قلبی عروقی و بیماریهای انعقادی خون، اثرات آنتی اکسیداتیو، درمان بیماریهای تنفسی وگوارشی، ا...

15 صفحه اول

Anti-nociceptive and anti-inflamatory activity of olive fruit extract

In Iranian traditional medicine, olive has been reported to have analgesic and anti-inflamatory effects. In the present study the anti-nociceptive and anti-inflamatory effects of olive fruit has been studied. In this study the methanolic and aqueous extract of the fruit with HER (Herbal to Extract Ratio) of 4.96% and 4.84% has been used and analgesic effect of this extract has been compared wit...

متن کامل

Anti-nociceptive and anti-inflamatory activity of olive fruit extract

In Iranian traditional medicine, olive has been reported to have analgesic and anti-inflamatory effects. In the present study the anti-nociceptive and anti-inflamatory effects of olive fruit has been studied. In this study the methanolic and aqueous extract of the fruit with HER (Herbal to Extract Ratio) of 4.96% and 4.84% has been used and analgesic effect of this extract has been compared wit...

متن کامل

Anti-nociceptive and anti-inflammatory effects of the methanolic extract of Opuntia humifusa stem

Objective: Opuntia humifusa (O. humifusa) Raf. has been used for the prevention and treatment of rheumatoid arthritis, inflammation, and cancer. Our study was designed to unveil the anti-nociceptive and anti-inflammatory effects of the methanolic extract of O. humifusa Raf stem (OHS).  Material and Methods: The anti-nociceptive effect was measured by hot plate, acetic acid-induced writhing, and...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
iranian journal of pharmaceutical research

جلد ۲۰۰۹، شماره ۷، صفحات ۲۲۳-۲۲۶

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023